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Progress in Pediatric Cardiology
Volume 27, Issue 1
, Pages 25-33
, December 2009
Pulmonary arterial hypertension associated with congenital heart disease
References
- . Pulmonary vascular disease. In: Freedom RM, Yoo S-J, Mikailian H, Williams WG editor. The natural and modified history of congenital heart disease. New York: Futura; 2004;p. 518
- . Surgical programme at Royal Alexandria Hospital, Sydney, for Papua New Guinea children with congenital heart disease, 1978–1994. J Paediatr Child Health. 2002;38:178–182
- . Pulmonary vascular disease in the developing world. Circulation. Oct 21 2008;118(17):1758–1766
- Clinical classification of pulmonary hypertension. J Am Coll Cardiol. Jun 16 2004;43(12 Suppl S):5S–12S
- Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol. 2009;54:S43–S54
- . Monoclonal endothelial cell proliferation is present in primary but not secondary pulmonary hypertension. J Clin Invest. 1998;101:927–934
- BMPR2 mutations in pulmonary arterial hypertension with congenital heart disease. Eur Respir J. 2004 Sep;24(3):371–374
- Transforming growth factor-beta receptor mutations and pulmonary arterial hypertension in childhood. Circulation. Feb 1 2005;111(4):435–441
- . The eisenmenger syndrome or pulmonary hypertension with reversed central shunt. BMJ (Clinical research ed.). 1958;2:701–709
- . Effects of infusion of acetylcholine on pulmonary vascular resistance in patients with pulmonary hypertension and congenital heart disease. Circulation. 1959;20:381–390
- . Effect of oxygen on pulmonary vascular resistance in patients with pulmonary hypertension associated with atrial septal defect. Circulation. 1959;20:66–73
- . Long-term physiologic observations in patients with ventricular septal defect and increased pulmonary vascular resistance (with 2 color plates). Adv Cardiol. 1974;11(00):108–122
- . Use of inhaled nitric oxide and acetylcholine in the evaluation of pulmonary hypertension and endothelial function after cardiopulmonary bypass. part 1 Circulation. 1993;88:2128–2138
- . Assessment and follow-up of patients with ventricular septal defect and elevated pulmonary vascular resistance. Am J Cardiol. Feb 1 1989;63(5):327–331
- . Does prostacyclin enhance the selective pulmonary vasodilator effect of oxygen in children with congenital heart disease?. Circulation. 1986;74(1):135–144
- . The Eisenmenger syndrome a clinical and physiological reappraisal. Am J Cardiol. 1971;28:679–692
- . Effect of long term oxygen treatment at home in children with pulmonary vascular disease. Br Heart J. 1986;55:385–390
- . Responsiveness to inhaled nitric oxide is a predictor for mid-term survival in adult patients with congenital heart defects and pulmonary arterial hypertension. Eur Heart J. Sep 2004;25(18):1651–1656
- . Vasomotor tone in the pulmonary vascular bed in patients with left to right shunts. Br Heart J. 1963;25:257–261
- . Pulmonary hypertension with special reference to the vasoconstrictive factor. Br Heart J. 1958;20:557–570
- . The pathology of hypertensive pulmonary vascular disease. Circulation. 1958;28:533–547
- . Lung biopsy in congenital heart disease: a morphometric approach to pulmonary vascular disease. Circulation. 1978;58:1107–1122
- . Pulmonary vascular disease in ventricular septal defect: structural and functional correlations in lung biopsies from 85 patients, with outcome of intracardiac repair. J Pathol. Jul 1987;152(3):157–168
- . Pulmonary vascular development: normal values of peripheral vascular structure. Am J Cardiol. Sep 1 1983;52(5):578–583
- . Die angeborenes Defekt der Kammerschiedewand des Herzen. Z Klin Med Suppl. 1897;32:1–28
- . The Eisenmenger syndrome or pulmonary hypertension with reversed central shunt. BMJ (Clinical research ed.). 1958;2:755–762
- . Inhaled nitric oxide and hemodynamic evaluation of patients with pulmonary hypertension before transplantation. J Am Coll Cardiol. 1995;25(7):1652–1664
- . Residual pulmonary vasoreactivity to inhaled nitric oxide in patients with severe obstructive pulmonary hypertension and Eisenmenger syndrome. Heart (British Cardiac Society). 2001;86:553–558
- . Vascular structure in lung tissue obtained at biopsy correlated with pulmonary hemodynamic findings after repair of congenital heart defects. Circulation. Apr 1984;69(4):655–667
- . Pulmonary vascular disease with congenital heart lesions; pathological features and causes. Circulation. 1981;64:873–877
- . Reversal of pulmonary hypertension associated with plexiform lesions in congenital heart disease; a case report. Pediatr Cardiol. 2002;23:182–185
- . Clinical course in ventricular septal defect. Circulation. 1977;56(Suppl l):I-56-69
- . Atrial septal defect. Br Heart J. Apr 1956;18(2):209–225
- . Natural history and prognosis of atrial septal defect. Circulation. May 1968;37(5):805–815
- . Atrial septal defect with pulmonary hypertension. Br Heart J. 1961;23:587–598
- . Frequency of severe pulmonary hypertension complicating “isolated” atrial septal defect in infancy. Am J Cardiol. Aug 1 2008;102(3):340–342
- . Pulmonary vascular disease in secundum atrial septal defect in childhood. Am J Cardiol. 1982;51:265–272
- . Isolated atrial septal defect with pulmonary vascular obstructive disease-long term follow up and prediction of outcome after surgical correction. Circulation. 1987;76(5):1037–1042
- Pulmonary hypertension in isolated secundum atrial septal defect: high frequency in young patients. Am Heart J. 1983;105:952–957
- . Pulmonary vascular disease in secundum atrial septal defect with pulmonary hypertension. Chest. 1986;89(5):694–698
- . Correction of isolated secundum atrial septal defect in infancy. Arch Dis Child. Oct 1981;56(10):784–786
- Unique features and prognosis of primum ASD presenting in the first year of life. Circulation. Nov 1994;90(5 Pt 2):II30–II35
- . Primary surgical closure of ventricular septal defect in the first year of life: results in 128 infants. J Am Coll Cardiol. May 1984;3(5):1269–1276
- . Prognosis for patients with ventricular septal defect and severe pulmonary vascular disease. Circulation. 1968;38:129–135
- . Ventricular septal defect with increased pulmonary vascular resistance. Am J Cardiol. 1974;33:403–409
- . Results of repair of ventricular septal defect. J Thorac Cardiovasc Surg. 1966;52(4):486–501
- . High-pressure, high resistance ventricular septal defect. Ann Thorac Surg. 1971;12:29–36
- . Ventricular septal defect: results after repair in infancy. Am J Cardiol. Jan 1977;39(1):66–71
- . Effects of surgical closure of ventricular septal defects upon pulmonary vascular disease. Br Heart J. Mar 1969;31(2):246–260
- . The hemodynamics in ventricular septal defect in childhood. Am Heart J. Dec 1965;70(6):732–738
- . Ventricular septal defect. In: Keith J, Vlad P, Rowe RD editor. Heart disease in infancy and childhood. New York: Macmillan Publishing Co; 1978;p. 320–379
- . Late results (30 to 35) years after operative closure of isolated ventricular septal defect from 1954 to 1960. Am J Cardiol. 1991;68:1491–1497
- . Cardiovascular abnormalities following surgery for left-to-right shunts. Observations in atrial septal defects, ventricular septal defects, and patent ductus arteriosus. Circulation. Dec 1969;40(6):785–801
- . Late results after surgical closure of ventricular septal defect in children. Scand J Thorac Cardiovasc Surg. 1980;14(2):145–151
- . Pulmonary vascular resistance during exercise late after repair of large ventricular septal defects. Relation to age at the time of repair. J Thorac Cardiovasc Surg. Jun 1995;109(6):1218–1224
- . Functional status of patients with large ventricular septal defect and pulmonary vascular disease 6 to 16
years after surgical closure of their defect in childhood. Br Heart J. Oct 1977;39(10):1093–1101 - . Exercise induced pulmonary vasoconstriction. Br Heart J. Jul 1983;50(1):59–64
- . Postoperative assessment of patients with ventricular septal defect and pulmonary hypertension. Response to intense upright exercise. Circulation. Oct 1973;48(4):864–874
- Long-term outcome of patients operated for large ventricular septal defects with increased pulmonary vascular resistance. Indian Heart J. Mar–Apr 2003;55(2):161–166
- . Pulmonary vascular disease in different types of congenital heart disease. Br Heart J. 1984;52:557–571
- . The pulmonary vascular bed in patients with complete transposition of the great arteries. Circulation. Mar 1976;53(3):539–543
- . Early onset of pulmonary vascular obstruction in patients with aortopulmonary transposition and intact ventricular septum. Circulation. May 1975;51(5):875–880
- . Pulmonary blood flow and left ventricular volumes in transposition of the great arteries and intact ventricular septum. Br Heart J. May 1973;35(5):521–526
- . Pulmonary vascular disease in transposition of the great vessels and intact ventricular septum. Circulation. Mar 1979;59(3):525–530
- . Progressive pulmonary hypertension after the arterial switch procedure. Am J Cardiol. 1994;73:620–621
- . Development of advanced pulmonary vascular disease in D-transposition of the great arteries after the neonatal arterial switch operation. Tex Heart Inst J. 1998;25(3):201–205
- . Pulmonary vascular disease in neonates with transposition of the great arteries and intact ventricular septum. Br Heart J. 1993;69:442–445
- . Prenatal features of restrictive foramen ovale and ductal constriction in D-transposition of the great arteries. Circulation. 1997;(I–129):724A
- . Mortality in potential arterial switch candidates with transposition of the great arteries. J Am Coll Cardiol. 1998;32:753–757
- . Congenital diseases of the heart: clinical–physiological considerations. In: Armonk, New York: Futura; 2001;p. 703
- . Pulmonary vascular disease in children with truncus arteriosus. Am J Cardiol. Dec 1 1984;54(10):1314–1320
- . Selection of patients with truncus arteriosus for surgical correction. Circulation. 1974;49:144–151
- . Aortic origin of the RPA: immediate resolution of severe pulmonary artery hypertension by surgical repair. Pediatr Cardiol. 1994;15:41–44
- . Atrioventricular septal defect. In: Freedom RM, Yoo S-J, Mikailian H, Williams WG editor. The natural and modified history of congenital heart disease. New York: Futura; 2004;
- . Pulmonary hypoplasia in Down's syndrome. N Engl J Med. 1982;307:1170–1173
- . Patterns of congenital heart disease and associated cardiac anomalies in children with Down syndrome. In: Marino B, Pueschel SM editor. Heart disease in persons with Down syndrome. Baltimore, Maryland: Paul H Brookes Publishing Co; 1996;p. 133–140
- . Role of hypoxia in determining pulmonary vascular resistance in infants with ventricular septal defects. Am J Cardiol. Sep 1967;20(3):346–349
- . Cross-sectional study of congenital heart disease among Tibetan children aged from 4 to 18
years at different altitudes in Qinghai Province. Chin Med J (Engl). Dec 20 2008;121(24):2469–2472 - . Prevalence of congenital cardiac anomalies at high altitude. J Am Coll Cardiol. Jul 1988;12(1):224–228
- . The heart and pulmonary circulation in children at high altitudes: physiological, anatomical, and clinical observations. Pediatrics. Oct 1964;34:568–582
- . Cardiopulmonary transition in the high altitude infant. High Alt Med Biol. Summer 2003;4(2):225–239
- . Pulmonary hypertension in children born and living at high altitudes. Am J Cardiol. 1963;11:143–149
- . Adaptation and acclimatisation in humans and animals at high altitude. Thorax. 1994;49:S9–S13
- . The heart and pulmonary circulation at high altitudes:helthyhighlanders and chronic moutain sickness. Circulation. 2007;115:1132–1146
- . Arterial remodeling: relation to hemodynamics. Can J Physiol Pharmacol. Jul 1996;74(7):834–841
- . Mechanical stress-initiated signal transduction in vascular smooth muscle cells in vitro and in vivo. Cell Signal. May 2007;19(5):881–891
- In utero placement of aortopulmonary shunts. A model of postnatal pulmonary hypertension with increased pulmonary blood flow in lambs. Circulation. Aug 1 1995;92(3):606–613
- . Alterations in TGF-beta1 expression in lambs with increased pulmonary blood flow and pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. Jul 2003;285(1):L209–L221
- . Expression of VEGF and its receptors Flt-1 and Flk-1/KDR is altered in lambs with increased pulmonary blood flow and pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. Jul 2003;285(1):L222–L231
- . Altered regulation of the ET-1 cascade in lambs with increased pulmonary blood flow and pulmonary hypertension. Pediatr Res. Jan 2000;47(1):97–106
- Fibroblast growth factor-2 expression is altered in lambs with increased pulmonary blood flow and pulmonary hypertension. Pediatr Res. Jan 2007;61(1):32–36
- . Role of hemodynamics in pulmonary vascular remodeling: implications for primary pulmonary hypertension. Am J Respir Crit Care Med. Feb 1999;159(2):361–364
- Changes in pulmonary blood flow affect vascular response to chronic hypoxia in rats. Circ Res. Apr 1983;52(4):432–441
- . Hemodynamic unloading leads to regression of pulmonary vascular disease. J Thorac Cardiovasc Surg. 2001;121:279–289
- . Effect of intracardiac repair on biosynthesis of thromboxane A2 and prostacyclin in children with a left to right shunt. Br Heart J. 1994;72:452–456
- . Thromboxane A2 and prostacyclin biosynthesis in children and adolescents with pulmonary vascular disease. Circulation. 1993;88:2117–2122
- . Increased plasma endothelin-1 in pulmonary hypertension: marker or mediator of disease. Ann Intern Med. 1991;114:464–469
- . Increased plasma levels of endothelin-1 after cardiopulmonary bypass in patients with pulmonary hypertension and congenital heart disease. J Thorac Cardiovasc Surg. 1993;106:473–478
- Plasma endothelin-1 in patients with left-to-right shunt. Am Heart J. 1995;130:537–542
- Plasma endothelin concentrations in patients with pulmonary hypertension associated with congenital heart defects. Evidence for increased production of endothelin in pulmonary circulation. Circulation. Dec 1991;84(6):2280–2285
- . Circulating endothelin in children with congenital heart disease. Br Heart J. 1993;69:233–236
- . Endothellin production in pulmonary circulation of patients with mitral stenosis. Circulation. 1994;89:2093–2098
- . Evaluation, risk stratification, and management of pulmonary hypertension in patients with congenital heart disease. Semin. Thorac. Cardiovasc. Surg. 2009;12:106–111
- The use of tolazoline hydrochloride as a pulmonary vasodilator in potentially fatal episodes of pulmonary vasoconstriction after cardiac surgery in children. Circulation. 1981;64(Suppl II):II-134-II-9
- . Pulmonary hypertensive crises following surgery for congenital heart defects in young children. Eur J Cardiothorac Surg. 1991;5:628–634
- Inhaled Nitric Oxide as a Preoperative Test (INOP Test I): the INOP Test Study Group. Circulation. Sep 24 2002;106(12 Suppl 1):I76–I81
- . The pulmonary vascular response to oxygen and its influence on operative results in children with ventricular septal defect. Pediatr Cardiol. 1982;3:41–46
- . The regression of pulmonary vascular disease after the creation of pulmonary stenosis. J Urol Nephrol (Paris). Dec 1961;42:722–734
- . Reversibility of plexogenic pulmonary arteriopathy following banding of the pulmonary artery. J Thorac Cardiovasc Surg. 1984;87:876–886
- . Discussion of high pressure, high resistance ventricular septal defect surgical results of closure through right atrium. J Thorac Cardiovasc Surg. 1971;12:37
- Successful reversal of pulmonary hypertension in Eisenmenger complex. Arq Bras Cardiol. 1997;68:279–280
- Double patch closure of ventricular septal defect with increased pulmonary vascular resistance. Ann Thorac Surg. 1998;66:1533–1538
- Flap valve double patch closure of ventricular septal defects in children with increased pulmonary vascular resistance. discussion -8 Ann Thorac Surg. Jan 2005;79(1):21–28
- Effect of body position changes on pulmonary gas exchange in Eisenmenger's syndrome. Am J Respir Crit Care Med. Apr 1999;159(4 Pt 1):1070–1073
- Nocturnal oxygen therapy in patients with the Eisenmenger syndrome. Am J Respir Crit Care Med. 2001;164:1682–1687
- . Inhaled nitric oxide in the management of congenital heart disease. Curr Opin Cardiol. Jan 1996;11(1):75–80
- . The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension. N Engl J Med. 1992;327:76–81
- Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension. Circulation. Jun 14 2005;111(23):3105–3111
- Diagnosis and differential assessment of pulmonary arterial hypertension. J Am Coll Cardiol. Jun 16 2004;43(12 Suppl S):40S–47S
- . Improvement of exercise capacity after nifedipine in patients with Eisenmenger syndrome complicating ventricular septal defect. Clin Cardiol. Dec 1991;14(12):957–961
- . Long-term hemodynamic effects of nifedipine on congenital heart disease with Eisenmenger's mechanism in children. Cardiovasc Drugs Ther. Apr 1992;6(2):183–186
- . Long-term prostacyclin for pulmonary hypertension with associated congenital heart defects. Circulation. 1999;99:1858–1865
- Usefulness of epoprostenol therapy in the severely ill adolescent/adult with Eisenmenger physiology. Am J Cardiol. Mar 1 2003;91(5):632–635
- Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study. Circulation. Jul 4 2006;114(1):48–54
- Long term effects of bosentan treatment in adult patients with pulmonary arterial hypertension related to congenital heart disease (Eisenmenger physiology): safety, tolerability, clinical, and haemodynamic effect. Heart (British Cardiac Society). May 2007;93(5):621–625
- Longer-term bosentan therapy improves functional capacity in Eisenmenger syndrome: results of the BREATHE-5 open-label extension study. Int J Cardiol. Jun 23 2008;127(1):27–32
- Long-term effect of bosentan in adults versus children with pulmonary arterial hypertension associated with systemic-to-pulmonary shunt: does the beneficial effect persist?. Am Heart J. Oct 2007;154(4):776–782
- . Effect of the oral endothelin antagonist bosentan on the clinical, exercise, and haemodynamic status of patients with pulmonary arterial hypertension related to congenital heart disease. Heart (British Cardiac Society). Nov 2005;91(11):1447–1452
- . Long-term oral bosentan treatment in patients with pulmonary arterial hypertension related to congenital heart disease: a 2-year study. Heart (British Cardiac Society). Mar 2007;93(3):350–354
- Bosentan for the treatment of pulmonary arterial hypertension associated with congenital heart defects. Eur J Clin Invest. Sep 2006;36(Suppl 3):25–31
- . Bosentan in Eisenmenger syndrome and chronic thromboembolic pulmonary hypertension. Eur J Clin Invest. Sep 2006;36(Suppl 3):39–43
- Long-term safety, tolerability and efficacy of bosentan in adults with pulmonary arterial hypertension associated with congenital heart disease. Heart (British Cardiac Society). Aug 2007;93(8):974–976
- Efficacy of bosentan in a small cohort of adult patients with pulmonary arterial hypertension related to congenital heart disease. Chest. Apr 2006;129(4):1009–1015
- . Initial experience with bosentan therapy in patients with the Eisenmenger syndrome. Am J Cardiol. Jul 15 2004;94(2):261–263
- . A retrospective study of bosentan in pulmonary arterial hypertension associated with congenital heart disease. Journal of the Medical Association of Thailand=Chotmaihet thangphaet. Feb 2008;91(2):196–202
- Bosentan for the treatment of pulmonary arterial hypertension associated with congenital cardiac disease. Cardiol Young. Jun 2006;16(3):268–274
- Adult patients with congenital heart disease and pulmonary arterial hypertension: first open prospective multicenter study of bosentan therapy. Am Heart J. Oct 2005;150(4):716
- Down patients with Eisenmenger syndrome: is bosentan treatment an option?. Int J Cardiol. Jun 23 2008;
- Safety experience with bosentan in 146 children 2–11
years old with pulmonary arterial hypertension: results from the European Postmarketing Surveillance program. Pediatr Res. Aug 2008;64(2):200–204 - Effects of long-term bosentan in children with pulmonary arterial hypertension. J Am Coll Cardiol. 2005;46(4):697–704
- Sitaxsentan therapy for pulmonary arterial hypertension. Am J Respir Crit Care Med. 2004;169:441–447
- Treatment of pulmonary arterial hypertension with the selective endothelin-A receptor antagonist sitaxsentan. J Am Coll Cardiol. May 16 2006;47(10):2049–2056
- Sitaxsentan for the treatment of pulmonary arterial hypertension: a 1-year, prospective, open-label observation of outcome and survival. Chest. Oct 2008;134(4):775–782
- . Response to bosentan in children with pulmonary hypertension. Heart (British Cardiac Society). May 2006;92(5):664–670
- . Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension. Circulation. 2002;105:2398–2403
- Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension. Circulation. 2003;108:2066–2069
- . Effects of chronic sildenafil in patients with Eisenmenger syndrome versus idiopathic pulmonary arterial hypertension. Int J Cardiol. Sep 3 2007;120(3):301–305
- . Beneficial effect of oral sildenafil therapy on childhood pulmonary arterial hypertension. twelve-month clinical trial of a single-drug, open-label, pilot study. Circulation. Jun 13 2005;
- . Sildenafil in Eisenmenger syndrome: safety first. Int J Cardiol. Sep 3 2007;120(3):314–316
PII: S1058-9813(09)00028-9
doi: 10.1016/j.ppedcard.2009.09.005
© 2009 Elsevier Ireland Ltd. All rights reserved.
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Progress in Pediatric Cardiology
Volume 27, Issue 1
, Pages 25-33
, December 2009
