Progress in Pediatric Cardiology
Volume 24, Issue 2 , Pages 89-99, January 2008

Oxygen Pressure Field Theory: A detailed description of vital gas exchange, at the capillary level for perfusionists

  • Gary Grist

      Affiliations

    • Corresponding Author InformationTel.: +1 816 234 3004; fax: +1 816 802 1245.

Section of Cardiovascular Surgery, The Children's Mercy Hospitals and Clinics, 2401 Gillham Rd., Kansas City, Missouri 64108 USA

Abstract 

Perfusionists are familiar with oxygen delivery and consumption of the Fick principle. Oxygen pressure field theory goes a step further by describing vital gas exchange at the capillary level. This article uses the Krogh cylinder model to describe the principles of the oxygen and carbon dioxide pressure fields, perfused capillary density, anoxic and hypercapnic lethal corners, axial oxygenation, oxygen loading strategy for deep hypothermic circulatory arrest, and the effect of edema on tissue oxygenation. These aspects of the oxygen pressure field theory can give the perfusionist additional insight into clinical perfusion applications.

Keywords: Oxygen, Capillary, Krogh cylinder, Perfusionist

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PII: S1058-9813(07)00154-3

doi:10.1016/j.ppedcard.2007.10.004

Progress in Pediatric Cardiology
Volume 24, Issue 2 , Pages 89-99, January 2008